CroNiMo High-Shear Mixer Granulators

CroNiMo High-Shear Mixer Granulators (HSMG) For Granulating Wet Masses of Pharmaceutical Compounds

About CroNiMo

The name CroNiMo is an assemblage of letters derived from three of the basic elements usually found in high quality stainless steels and other exotic alloys (Chromium, Nickel and Molybdenum). As its name implies, CroNiMo is committed to producing machinery for the pharmaceutical industry that blends high quality European craftsmanship and their knowledge of working with Stainless Steel. This Austrian-Dutch family-run, Argentinean company has slowly and quietly built up a strong global customer base because of their commitment to quality and the competitive price position of its products. Their products include High Shear Granulators, Mills, Coaters and Fluid Bed Dryers as well as completely integrated systems.

CroNiMo High Shear Granulators:

For formulation development purposes. The CroNiMo Model MB5 high shear granulator is designed with a standard 5 liter bowl but has options for 2, 10 and 15 liter interchangeable bowls. The standard controls include a simple push button based system with variable speed chopper and mixer drives. The MB5 is provided with a cart with large wheels to provide mobility, safety and a convenient location for mounting the control cabinet and a variety of options that may be selected.

All product contact parts as standard are constructed of 316 Stainless Steel and and polished to a #7 mirror finish with a surface roughness of Ra. < 0.20u. Non-product contact parts are 304 Stainless Steel with a #4 finish.

The control systems available are dependent upon the customer’ specified level of system functional control and the sophistication level of data collection and analysis to be performed by the MB5 on board system.

The CroNiMo MB5 (Multi-Bowl 5) can be provided with a wide variety of mechanical options , such as bowl jackets, lighted bowl, liquid preparation system, heater/chiller units, vacuum loading, Stainless Steel filter housing and other features. Some of the options are not available on the 2 or 5 liter bowls due to size restrictions.

 

The Cronimo production high shear granulators include the following bowl sizes: 25, 80, 125, 250, 400, 600 and 1000 liters. Each of these machines can be designed for “In-Room” construction or “Thru-The-Wall” construction for either non-explosion or explosion proof rated environments. The control systems selected can be very simple standard PLC-based pushbutton controls to a fully automated system using either Allen Bradley or Siemens based controls including a touchscreen HMI. A fully automated system can be offered in full compliance with 21 CFR Part 11 and GAMP IV, including the required documentation. All producttion sized granulators have available as an option the Cronimo TTM^™ True Torque Measurement system for end point detection.

 

 

 

 

 

 

 

AC Compacting LLC
1577 Livingston Avenue, Post Office Box 7266
North Brunswick, NJ 08902-7266
Tel: 732-249-6900 / Tel: 800-524-0183 / Fax: 732-249-6909