Variable Density Extrusion For the Laboratory

Only the Caleva VDE Variable Density Extruder™ can offer a selection of extruder die apertures and bore lengths for both radial and axial extrusion methods.

With aperture diameters from 0.4 – 2.0mm and bore lengths from 0.5 – 8.0mm, the optimal length to diameter ratio (L:D ratio) can be selected to produce the ideal density extrusions to suit your application.

The unique ability of the VDE™ to produce extrusions using either the Axial or Radial methods, coupled with the range of die L:D ratios allows for quick and easy laboratory evaluation of various densities and formulations. There is nothing else available that offers this degree of flexibility and ease of use in a single piece of equipment.

The VDE™ from Caleva, for the development of pellets by Extrusion and Spheronization. The most flexible and productive laboratory extruder available. The only bench-top extruder with variable die diameter and depth with both radial and axial extrusion!

A short YouTube video showing the Caleva VDE™ in operation can be found here.

• Ability to control the density of the extrudate.
• Radial and axial extrusion in a single bench-top unit.
• High flexibility according to requirements of the formulation.
• Reduce patient dosing frequency by increasing product density.
• A wide range of apertures and depths are available.
• Comparative trials have shown significant yield benefits.
• Trials produced average usable yield with a higher density result.
• Toolless assembly and disassembly for cleaning.
• All product contact components are manufactured in 316 stainless steel, and cGMP compliant polymers.
• Product can be heated or cooled as required.
• Heat of extrusion can be partially or completely removed, depending on formulation and configuration.
• Operating parameters are directly controlled by the user.

• Extrusion rates up to 27kg/hr* on a radial screen and 20kg/hr* on an axial screen.
• All product contact components are manufactured in316 stainless steel, and cGMP compliant polymers.
• Safety interlocked.
• Operating parameters are directly controlled by the user via front panel controls.
• Jacketed screw casing allows the product to be heated or cooled as required. Heat of extrusion can be partially or completely removed, depending on formulation and configuration.

Utilities:

• 110 volt, single phase, 60 HZ.
• Liquid heating/cooling medium.

*Figures given here are for comparison purposes only. The actual production rate will depend on the machine’s configuration and the material being extruded.

THERE IS A BROAD RANGE OF EXTRUDER APERTURES AND DEPTHS AVAILABLE:

• Diameters between 0.4 and 2.0mm.
• Depths between 0.5mm and 8mm.