The Caleva Mixer Torque Rheometer is well established as a valuable formulation development, formulation research and, production quality control tool. It will uniquely provide you with quantitative and reproducible measurements of the rheology of a wet mass. Having this information will enable you to optimize your formulations in the least possible time. It will enable you to investigate product and excipient quality issues in a quantitative and meaningful way.
You will obtain reproducible data regardless of whether you have simple or complex formulations, with different binders and different mixing times. The reproducible figures generated can be incorporated into formulation development and production quality control saving both time and cost. The data can be used as part of scale-up and the instrument can also be used for quality control in production. The MTR-3 is designed to enable the user to quantify the consistency properties of a wet mass.
Mixer Torque Rheometer
Determine the Optimum Powder to Binder Ratio
Multiple Addition Test
Binder liquid is added to a dry powder mix and the consistency is measured as the mixing and addition of binder progresses.
The consistency of the mix is measured at regular periods so that the relationship between the amount of liquid binder added to the mix and the consistency in the resulting formulation can be accurately shown.
Variable Mix Time Test
How Long Should I Granulate my Materials?
It is well-known that a minimum amount of mixing is required to ensure consistent and repeatable product characteristics. What is often less considered is the possibility of over-mixing the product so that the characteristics of the resulting formulation undergo a change. It is important to understand this and to have data to show what is likely to happen with excessive mixing. The Mixer Torque Rheometer will give you this data. This type of test is again used in formulation development but more generally in scale up to production from the laboratory and also it has been used to solve production issues as they arise.
Ensuring Consistency During Scale Up
A direct consistency measurement of a small sample (generally around 40 g) taken from a process as it is ongoing. This allows for accurate comparisons to be made quickly, accurately, and repeatable way.